poliglecapronone

Poliglecaprone, commonly known by the trade name Monocryl, is a synthetic absorbable monofilament suture material used in medicine. It is a copolymer of glycolide and epsilon-caprolactone (poliglecaprone 25), produced by ring-opening polymerization. The material is designed to provide adequate initial tensile strength during the early healing period, then gradually hydrolyze and be absorbed by the body.

The monofilament structure offers smooth passage through tissue with low drag and minimal tissue reaction compared with multifilament sutures. Poliglecaprone 25 is described as a fast-absorbing suture, with a predictable absorption profile. The exact rate of absorption and loss of strength depend on implantation site, tissue type, and patient factors; the suture is generally fully absorbed within a few months.

Indications for use include soft tissue approximation and suturing, subcutaneous closures, mucosal repairs, and other closures where temporary support is sufficient. It is widely employed in various surgical fields such as general surgery, obstetrics and gynecology, urology, ophthalmology, and plastic surgery. It is not ideal for high-tension closures or contaminated wounds where longer-lasting support is required; slower-absorbing alternatives may be preferred in those situations.

Safety and handling considerations are similar to other synthetic absorbable sutures: it is designed to be biocompatible with relatively low tissue reactivity and is available in multiple gauges to suit different surgical needs. Poliglecaprone is one of several absorbable sutures used to tailor tissue healing and cosmetic outcomes across procedures.

Note: spelling variants such as poliglecapronone may appear in some texts; the commonly used material is poliglecaprone 25.