Monocryl

Monocryl is the trade name for poliglecaprone 25, a synthetic absorbable monofilament suture used for soft tissue closure in surgery. It is manufactured by Ethicon, a subsidiary of Johnson & Johnson. The suture is made from poliglecaprone 25, a copolymer of glycolide and epsilon-caprolactone, designed to provide relatively rapid absorption with low tissue reaction.

Monocryl is intended for closures where quick loss of tensile strength is acceptable and rapid absorption is advantageous. It is commonly used for subcutaneous tissue and mucosal closures, and is popular in cosmetic facial repairs and other soft-tissue applications. It is available in plain form and in Monocryl Plus variants, which are triclosan-coated to reduce bacterial colonization on the suture.

Handling characteristics include smooth tissue passage and low drag, with predictable absorption. Monocryl provides adequate initial strength for short-term support but does not maintain long-term tensile strength, making it unsuitable for wounds requiring prolonged mechanical support. It is typically chosen for areas where rapid healing is expected and a minimal tissue reaction is desired.

Limitations include higher cost relative to some alternatives and the need for appropriate technique to ensure reliable knot security with a monofilament. It is generally avoided in contaminated or infected wounds where longer-lasting sutures may be preferable.

Monocryl and related poliglecaprone 25 sutures are widely used in general surgery, plastic and reconstructive procedures, obstetrics and gynecology, and urology, chosen according to tissue type, required duration of support, and surgeon preference.