degenerationrelated
Degeneration-related describes processes in which biological tissues lose structure and function progressively. In medicine, degeneration-related conditions are characterized by chronic, often age-associated decline rather than acute injury. The term encompasses diseases, syndromes, and non-diagnostic states in which cells or tissues progressively deteriorate, leading to impaired organ performance.
Common domains include neurodegenerative diseases (Alzheimer's disease, Parkinson's disease, Huntington's disease), degenerative joint and spine conditions
Causes and mechanisms: aging, genetic factors, metabolic disturbances, oxidative stress, chronic inflammation, and environmental exposures contribute.
Diagnosis and management: diagnosis relies on clinical evaluation supported by imaging, biomarkers, and functional tests. Management
Research directions: prevention strategies focus on risk factor modification and early detection; advances in genetics, cellular