eicelreserve

Eicelreserve, commonly translated as ovarian reserve, refers to the remaining quantity and quality of oocytes in the ovaries and their potential to mature and be fertilized. It reflects the size of the primordial follicle pool and the competence of oocytes, and it generally declines with age. The reserve is established before birth and gradually diminishes during a woman’s reproductive years, with an accelerated decline after the mid-30s and eventual menopause when functional oocytes are depleted.

Assessment of eicelreserve relies on a combination of indicators. Anti-Müllerian Hormone (AMH) levels, the antral follicle count (AFC) by transvaginal ultrasound, and basal follicle-stimulating hormone (FSH) are commonly used tests. AMH and AFC correlate with the remaining pool of recruitable follicles, while FSH can rise when reserve is diminished. However, no single test precisely predicts natural fertility, and results can vary with age, assay methods, and individual factors. Clinicians interpret these markers together with clinical history.

Clinical relevance includes fertility counseling, planning for assisted reproduction, and decisions about fertility preservation in individuals facing gonadotoxic treatments such as chemotherapy. A lower eicelreserve may influence strategies for ovarian stimulation in IVF and the consideration of oocyte, embryo, or ovarian tissue cryopreservation. It is important to recognize that reserve is only one determinant of fertility; oocyte quality, partner factors, and reproductive health also play critical roles. Research continues to refine markers and interventions aimed at preserving or extending ovarian reserve.