angulaarkiiruse

Angulaarkiiruse, also known as *Angularis* or *Angularis disease*, is a rare and poorly understood condition characterized by the development of angular cheilitis and associated oral lesions. The term originates from the Greek words *angulos* (meaning "corner") and *cheilitis* (inflammation of the lips), reflecting its primary symptom: inflammation and fissuring at the corners of the mouth.

The exact etiology of angulaarkiiruse remains unclear, but it is often linked to secondary infections, nutritional deficiencies, or underlying systemic conditions. Common contributing factors include:

- **Candidal infection**: Overgrowth of *Candida albicans*, a yeast-like fungus, is frequently observed in affected individuals, particularly in immunocompromised patients or those with diabetes.

- **Nutritional deficiencies**: Insufficient intake of riboflavin (vitamin B2), iron, or zinc can predispose individuals to angular cheilitis.

- **Mechanical irritation**: Prolonged lip licking, denture use, or poor-fitting dental appliances may exacerbate the condition.

- **Systemic diseases**: Conditions such as HIV/AIDS, malnutrition, or autoimmune disorders may contribute to its development.

Symptoms typically include redness, swelling, and painful cracks at the corners of the mouth, sometimes accompanied by scaling or crusting. Diagnosis is often clinical, though laboratory tests (such as fungal cultures or blood tests for deficiencies) may be performed to confirm underlying causes.

Treatment focuses on addressing the root cause. Antifungal creams (e.g., clotrimazole or nystatin) are commonly prescribed for candidal infections, while nutritional supplements may be recommended for deficiencies. Proper oral hygiene, avoiding lip licking, and adjusting dental appliances can also aid recovery. In persistent or severe cases, consultation with a dermatologist or specialist is advised.

While angulaarkiiruse is generally not life-threatening, its recurrence may indicate an underlying health issue, emphasizing the importance of thorough evaluation and management. Further research is needed to fully elucidate its pathogenesis and optimize therapeutic approaches.