SODinhibitable
SODinhibitable is a descriptor used in biochemistry and physiology to denote a process, reaction, or signaling event whose activity is reduced by the action of superoxide dismutase (SOD). When a process is described as SODinhibitable, the involvement of superoxide radicals is suggested because their dismutation by SOD diminishes the observed outcome. The term may appear as SOD-inhibitable or SODinhibitable in the literature.
The concept is commonly applied in studies of reactive oxygen species and redox signaling to distinguish mechanisms
Experimental usage typically involves comparing a system's activity with and without the addition of SOD or
Limitations include the fact that SOD is not a universal inhibitor and may affect other components of
See also: superoxide dismutase, reactive oxygen species, oxidative stress, redox signaling.