Il2

IL2 may refer to several distinct topics in biology, aviation, and gaming.

Interleukin-2, often abbreviated IL-2, is a cytokine that plays a central role in the regulation of white blood cells during immune responses. It is produced primarily by activated CD4+ T cells and, to a lesser extent, by other immune cells. IL-2 promotes T cell proliferation, survival, and differentiation, and it influences the balance between effector and regulatory T cell populations through signaling via the IL-2 receptor, which comprises different subunits. The IL2 gene encodes this protein in humans and is located in the chromosome 4q27 region, an area associated with other immune-related genes such as IL-21. Clinically, recombinant IL-2 has been used in certain cancer therapies to boost immune activity, though its use can be limited by toxicity and complex patient responses.

Ilyushin Il-2 Shturmovik refers to a Soviet ground‑attack aircraft developed during World War II. First flown in 1939 and entering service in 1941, it was designed with heavy armor to protect the crew and vital systems during low-altitude attacks against ground targets. The Il-2 had a two‑person crew and served extensively on the Eastern Front, earning a reputation for durability and effectiveness in close air support. Production totaled in the tens of thousands, making it one of the most produced military aircraft of its era and a symbol of Soviet air power in the war.

IL-2 Sturmovik is a long-running series of PC flight simulators focusing on World War II aviation, developed by Maddox Games and published by 1C Company. Beginning with the first title released in 2001, the series emphasizes realistic flight dynamics, authentic aircraft models, and historically informed combat scenarios, and has evolved to include numerous stand-alone and expansion releases as well as modern graphics and VR support.