immunerelated

Immunerelated is an adjective used to describe things connected with the immune system, its components, and their functions in health and disease. It encompasses biology, medicine, and public health topics that involve immune responses, regulation, and interactions with pathogens, tumors, vaccines, and transplanted tissues. The immune system comprises innate and adaptive branches, including barriers such as skin and mucosa, phagocytic cells, lymphocytes (T cells, B cells), antibodies, cytokines, and regulatory networks that coordinate defense and tolerance.

Immunerelated topics include normal immune development and homeostasis, mechanisms of antigen recognition, inflammation, and immunoregulation. Clinically important areas include autoimmune diseases in which self-tolerance fails, immunodeficiencies that impair defense, allergic and hypersensitivity reactions, and infectious diseases where immune responses determine outcomes. Vaccines and vaccinology are central to training and shaping protective immunity, while immunotherapies exploit immune mechanisms to treat disease, notably in cancer with checkpoint inhibitors and cellular therapies such as CAR-T, or in transplantation and infectious disease control.

Research methods used in immunerelated work range from serology and flow cytometry to genomic and proteomic approaches, enabling study of immune cell populations, signaling pathways, and host–microbe interactions. The field emphasizes the balance between protective immunity and immunopathology, seeking strategies that enhance defense while minimizing adverse effects, including immune-related adverse events in treatment.