telomeraza
Telomerase is a ribonucleoprotein complex that is responsible for the maintenance of telomeres, the protective caps at the ends of eukaryotic chromosomes. Telomeres are essential for the stability and integrity of the genome, as they prevent the loss of genetic information during cell division. Telomerase consists of two main components: the telomerase RNA (TERC) and the telomerase reverse transcriptase (TERT). TERC provides the template for telomere elongation, while TERT catalyzes the addition of DNA nucleotides to the 3' end of the telomere.
Telomerase activity is typically high in germ cells, embryonic cells, and some cancer cells, where it is
Telomerase has been a subject of intense research due to its potential implications in aging, cancer, and
The regulation of telomerase activity is complex and involves multiple mechanisms. TERT expression is controlled at