nikotínamid

Nikotínamid, also known as niacinamide, is a form of vitamin B3. It is one of the two principal forms of vitamin B3, the other being nicotinic acid. Nikotínamid is essential for various bodily functions.

It plays a crucial role in cellular metabolism, particularly in the production of energy. It is a precursor to coenzymes NAD+ and NADP+, which are involved in hundreds of enzymatic reactions. These coenzymes are vital for DNA repair, cell signaling, and the synthesis of fatty acids and cholesterol.

Dietary sources of nikotínamid include meat, fish, eggs, dairy products, and many vegetables. It is also commonly added to fortified foods like cereals and bread. The body can also synthesize nikotínamid from tryptophan, an amino acid.

In addition to its metabolic roles, nikotínamid has gained attention for its topical applications in skincare. It is known to have anti-inflammatory properties, help improve skin barrier function, reduce the appearance of pores, and regulate oil production. It is often found in serums, moisturizers, and cleansers.

A deficiency in vitamin B3 can lead to pellagra, a disease characterized by dermatitis, diarrhea, and dementia. However, severe deficiencies are rare in developed countries due to the widespread availability of fortified foods and a varied diet. Nikotínamid is generally considered safe, with high doses potentially causing mild side effects like flushing, though this is less common with nikotínamid compared to nicotinic acid.