hyperurikemie
Hyperurikémie, or hyperuricemia, is a condition defined by persistently elevated levels of uric acid in the blood. Uric acid is the end product of purine metabolism in humans. Because humans lack the enzyme uricase, uric acid has limited solubility; when concentrations exceed the solubility threshold, crystals may form in joints, soft tissues, or kidneys.
The condition results from either increased production of uric acid, decreased renal excretion, or a combination
Most people with hyperuricemia are asymptomatic. When urate crystals deposit in joints, a gout attack can occur,
Diagnosis relies on serum uric acid measurement, with interpretation guided by clinical context. A single elevated
Management focuses on lowering uric acid to target levels, treating gout flares, and addressing contributing factors.