autosamplere

Autosamplere is not a widely used term in analytical science. It most likely represents a misspelling or brand-specific variant of autosampler, an automated sample introduction device used in chromatography and related analytical techniques. An autosampler automates the loading and injection of sample vials into an instrument, enabling hands-free operation and increased throughput.

A typical autosampler comprises a vial tray or carousel, a robotic gripper or arm, a syringe-based injector with a defined needle, a washing station, and often a cooling or heating system to preserve sample integrity. The tray holds dozens to hundreds of vials; the robot retrieves a vial, the syringe aspirates a defined volume, and the injector delivers the sample into the analytical instrument. Modern units may include barcode or RFID readers to track samples and software to control injection order, volumes, temperatures, rinsing cycles, and run sequences. They are commonly integrated with high-performance liquid chromatography (HPLC), gas chromatography (GC), or hyphenated systems such as LC-MS or GC-MS, enabling unattended analytical runs.

Applications span pharmaceutical development, environmental monitoring, clinical chemistry, food safety, and forensic analysis. Benefits include higher throughput, improved precision and reproducibility, reduced analyst exposure to solvents and samples, and minimized manual handling.

Limitations and considerations include potential carryover between injections, especially with viscous or dirty samples; the need for regular cleaning and calibration of syringe volumes; solvent compatibility with the system; and the importance of robust data management and instrument software to track samples and results. In practice, the correct term is autosampler, and autosamplere may appear as an uncommon variant or error.