Vananemisest
Vananemisest is the Estonian term for aging, the process by which organisms accumulate biological changes over time that can reduce function and increase disease risk.
In humans, aging results from a complex mix of genetic, environmental, and lifestyle factors that affect cells
Key mechanisms include telomere shortening, DNA damage, cellular senescence, epigenetic changes, mitochondrial dysfunction, proteostasis impairment, and
Aging leads to visible signs such as hair graying and skin changes, and to functional declines like
Demographically, population aging arises from longer life expectancy and lower birth rates and has implications for
Public health responses focus on lifelong health, with regular physical activity, nutritious diet, avoidance of smoking,
Research in aging spans biology, epidemiology, and clinical trials, exploring interventions including exercise, caloric restriction mimetics,
The goal is to extend healthspan, the period of life in good health, rather than simply lifespan.
Ethical and social issues involve equitable access to therapies, the economic impact of aging populations, and