Nuspojava

Nuspojava is a term used in pharmacology and medicine to denote adverse or undesirable effects caused by a drug, vaccine, or other medical intervention. It covers a spectrum from mild, self-limiting symptoms to severe, potentially life-threatening events. The concept is closely related to adverse drug reactions and side effects, but nuspojava often emphasizes the broader safety profile of a treatment in practice and on labeling.

Nuspojava can be predictable and dose-dependent (for example nausea, fatigue, dry mouth) or unpredictable and idiosyncratic (for example severe allergic reactions). Risk factors include age, genetics, organ function, interactions with other drugs, and comorbidities.

Assessment of nuspojava is central to pharmacovigilance. Clinicians report suspected events to national or regional systems; causality assessment tools help determine the likelihood that the drug caused the event. Management focuses on patient safety: discontinuing or reducing the drug, switching to alternatives, treating the reaction, and educating patients to recognize warning signs.

Preventive measures include rigorous safety testing, clear labeling, dosage recommendations, and ongoing post-marketing surveillance to identify rare or long-term harms. The term itself is used in several Slavic language contexts and is often translated as "side effects" or "adverse reactions" in multilingual texts. See also Adverse drug reaction, Pharmacovigilance, Side effect.