zsírbeáramlás

zsírbeáramlás is a Hungarian term that translates to "fat influx" or "fat infiltration" in English. It refers to the process where excessive amounts of fat accumulate in tissues or organs that are not typically designated for fat storage. This phenomenon can occur in various parts of the body and is often associated with metabolic dysfunction and disease.

The most common site of zsírbeáramlás is the liver, leading to non-alcoholic fatty liver disease (NAFLD). In this condition, fat droplets accumulate within liver cells, impairing their function. This can progress to inflammation (non-alcoholic steatohepatitis or NASH), fibrosis, cirrhosis, and even liver cancer. Other organs where zsírbeáramlás can occur include the pancreas, heart muscle (cardiac steatosis), skeletal muscle, and kidneys.

Several factors can contribute to zsírbeáramlás. Obesity and insulin resistance are primary drivers. High-caloric diets rich in saturated fats and refined carbohydrates, coupled with a sedentary lifestyle, promote excessive fat intake and hinder its efficient utilization or storage. Genetic predisposition also plays a role in an individual's susceptibility. Hormonal imbalances, such as those seen in Cushing's syndrome, can also lead to ectopic fat deposition.

The consequences of zsírbeáramlás extend beyond the affected organ. It is strongly linked to systemic metabolic disorders like type 2 diabetes, dyslipidemia (abnormal blood lipid levels), and cardiovascular disease. The inflammatory and oxidative stress associated with ectopic fat deposition can damage cells and tissues throughout the body. Diagnosis typically involves imaging techniques like ultrasound or MRI, and sometimes liver biopsy for confirmation and staging. Management strategies focus on lifestyle modifications, including weight loss, a balanced diet, and regular physical activity, alongside addressing underlying medical conditions.