vetstapeling

Vetstapeling is a Dutch term that refers to the accumulation of fat in adipose tissue. In physiology it describes the expansion of fat stores in response to a sustained positive energy balance, and it can occur through two linked processes: hypertrophy, where existing fat cells (adipocytes) enlarge as they store more triglycerides, and hyperplasia, where new adipocytes form from precursor cells to accommodate additional fat.

The rate and pattern of vetstapeling are influenced by hormonal and metabolic signals, including insulin, leptin, adiponectin, cortisol, and growth hormone. Dietary intake, physical activity, and genetic factors all contribute to the likelihood of fat accumulation. The distribution of fat matters for health: subcutaneous fat is generally less strongly linked to metabolic risk than visceral fat, which surrounds internal organs and is more closely associated with insulin resistance, inflammation, and metabolic syndrome.

Vetstapeling is a central topic in obesity research and in veterinary settings. In humans, it relates to weight gain, obesity-related diseases, and responses to diet and exercise interventions. In animals, it is monitored in the context of nutrition, growth, and production efficiency.

Measurement of fat accumulation uses imaging methods such as MRI or CT scans, dual-energy X-ray absorptiometry, ultrasound, or skinfold assessments. Tissue-level studies examine adipocyte size, adipose tissue inflammation, and adipokine release. Management typically involves caloric balance, physical activity, and, in some cases, pharmacological or surgical options for weight reduction.