immuncheckpointblockad
Immuncheckpointblockad, commonly referred to as immune checkpoint blockade, is a form of cancer immunotherapy that aims to boost the body's immune response against tumors. It achieves this by blocking inhibitory signals that restrain T cell activity, allowing T cells to recognize and attack cancer cells more effectively. The term may be encountered in various spellings, but refers to the same therapeutic concept.
The mechanism involves targeting immune checkpoints—regulatory pathways such as CTLA-4, PD-1, and PD-L1 that normally help
Indications span several cancers, including melanoma, non-small cell lung cancer, renal cell carcinoma, urothelial carcinoma, and
Safety profiles feature immune-related adverse events affecting skin, gut, endocrine, liver, and other organs, ranging from