betatrikalsiumfosfat

Betatrikalsiumfosfat, also known as β‑tricalcium phosphate, is a calcium phosphate compound with the chemical formula Ca_3(PO_4)_2. The β polymorph is distinguished from the more common α‑tricalcium phosphate by its crystal structure, which is more stable at physiological temperatures. It is a white to off‑white, fine powder that is soluble in acids and partially soluble in water, with a typical density of about 2.7 g cm^−3.

The material is biologically inert and exhibits excellent biocompatibility, making it a popular bone substitute in orthopedic and dental applications. In medicine, β‑tricalcium phosphate is used as a scaffold for bone grafting, as a delivery vehicle for drugs, and as a filler for cavities in endodontics. Its resorbability in vivo enables gradual replacement by native bone tissue without weakening the skeleton.

Commercially, it is manufactured via high‑temperature sintering of calcium carbonate and phosphate precursors, often followed by milling to achieve the desired particle size. The powder can be processed into porous sponges, pellets, or pastes, and is sometimes mixed with polymers or bioactive agents to tailor mechanical properties and degradation rates.

Research into β‑tricalcium phosphate has explored its role in stimulating osteogenic differentiation, its antibacterial properties when doped with ions such as silver or copper, and its potential as a carrier for growth factors. Because of these attributes, the compound continues to be a focus of materials science and medical device development.