arteriosklerósa

Arteriosklerósa, commonly known as hardening of the arteries, is a medical condition characterized by the thickening, hardening, and loss of elasticity of the walls of arteries. This process typically occurs over many years and can affect arteries throughout the body, including those supplying the heart, brain, and limbs.

The primary underlying mechanism of arteriosclerosis is the buildup of plaque, a fatty deposit containing cholesterol, cellular waste products, calcium, and fibrin, on the inner walls of the arteries. This accumulation, known as atherosclerosis, narrows the arterial lumen, restricting blood flow. Over time, the plaque can harden and calcify, further reducing the artery's flexibility.

Several risk factors contribute to the development and progression of arteriosclerosis. These include high blood pressure, high cholesterol levels, smoking, diabetes, obesity, a sedentary lifestyle, and a family history of heart disease. Age is also a significant factor, as the risk of arteriosclerosis increases with advancing age.

The consequences of arteriosclerosis depend on which arteries are affected. If arteries supplying the heart become narrowed, it can lead to angina (chest pain) or a heart attack. Blockage of arteries in the brain can result in a stroke. Arteriosclerosis in the limbs can cause peripheral artery disease, leading to pain, cramping, and difficulty walking.

Diagnosis of arteriosclerosis often involves a physical examination, blood tests to check cholesterol and blood sugar levels, and imaging tests such as ultrasound, CT scans, or angiography to visualize the arteries. Treatment aims to slow or halt the progression of the disease and prevent complications. This typically includes lifestyle modifications such as dietary changes, regular exercise, and smoking cessation, along with medications to manage blood pressure, cholesterol, and diabetes. In some cases, surgical procedures like angioplasty or bypass surgery may be necessary to restore blood flow.