SBMA

SBMA is an acronym that can refer to more than one organization or condition, depending on the context. The two most common uses are spinal and bulbar muscular atrophy, also known as Kennedy disease, and the Subic Bay Metropolitan Authority in the Philippines.

Spinal and bulbar muscular atrophy (SBMA), or Kennedy disease, is a hereditary neurodegenerative disorder caused by a CAG trinucleotide repeat expansion in the androgen receptor gene on the X chromosome. It predominantly affects males, with onset typically in adulthood. The disease leads to progressive weakness and atrophy of limb and bulbar muscles, muscle cramps, and fasciculations, along with reduced reflexes. Some individuals develop endocrine features such as gynecomastia, reduced body hair, and infertility, reflecting partial androgen insensitivity. Sensory function is usually preserved early in the course. Diagnosis relies on clinical presentation and genetic testing that confirms the expanded CAG repeats in AR. There is no cure, and treatment focuses on symptom management and supportive care, including physical and occupational therapy, respiratory support if needed, and monitoring for complications.

Subic Bay Metropolitan Authority (SBMA) is a government-owned and controlled corporation in the Philippines responsible for the Subic Bay Freeport Zone. Created by Republic Act 7227, the Bases Conversion and Development Act of 1992, SBMA oversees the conversion of the former Subic Bay naval facility into a mixed-use economic and tourism zone. The authority manages investments, infrastructure, port operations, environmental protection, and regulatory affairs within the freeport. It is governed by a board headed by an administrator, and it offers incentives to locators such as tax and customs privileges to promote economic activity and job creation.