OrthostaseTremor
OrthostaseTremor, commonly referred to as orthostatic tremor, is a rare movement disorder characterized by a high-frequency tremor of the legs that emerges when a person stands still and is relieved by walking, sitting, or lying down. The tremor is typically most noticeable as a feeling of unsteadiness rather than a visible shake. Electrophysiological testing often detects a tremor frequency in the 13 to 18 Hz range.
Clinical features include onset in middle to older adulthood, gradual progression, and marked instability when standing.
Diagnosis relies on history and physical examination, supported by electrophysiological studies such as surface or intramuscular
Etiology and pathophysiology are not fully understood. Evidence suggests a central generator involving brainstem and cerebellothalamocortical
Treatment aims at symptom relief. No disease-modifying therapy is established. Low-dose benzodiazepines (eg, clonazepam) and anticonvulsants