Gewebemarge

Gewebemarge, also known as tissue margin, refers to the border or edge of excised tissue during surgical procedures, particularly in oncological and biopsic surgeries. It is a critical factor in determining the completeness of a tumor removal and the likelihood of residual disease. The goal of achieving a clear or negative margin is to ensure that no cancerous or abnormal cells are left at the edges of the excised tissue.

In surgical oncology, the evaluation of gewebemarge involves histopathological examination. The pathologist assesses whether the margins are free of tumor cells (negative margins) or if tumor cells are present at the edge (positive margins). A positive margin often indicates the need for additional treatment, such as further surgery or adjuvant therapy, to reduce the risk of recurrence.

The size and status of the gewebemarge are influenced by factors such as tumor size, location, invasiveness, and surgical technique. Surgeons aim to remove tissue with an adequate margin to minimize the chances of local recurrence while preserving as much healthy tissue as possible to maintain function and aesthetics.

Understanding the concept of gewebemarge is essential in cancer management, guiding treatment decisions and prognostic evaluations. While the ideal margin varies depending on the type of tumor and its location, achieving clear margins is generally associated with improved clinical outcomes in many cancer treatments.