CaCO3na

CaCO3na refers to nanoscale calcium carbonate particles or nanostructured calcium carbonate materials. It is not a single chemical compound with a fixed stoichiometry, but a class of CaCO3-based nanomaterials designed to exploit the high surface area and tunable properties of nanoscale calcium carbonate.

Calcium carbonate naturally forms as calcite, aragonite, and vaterite. At the nanoscale, CaCO3 nanomaterials can adopt one or more of these polymorphs, often with mixed-phase domains. The surface of CaCO3na is commonly functionalized with polymers, silanes, or biomolecules to improve dispersion, stability, or compatibility with composites and biological systems.

Synthesis methods include controlled precipitation of Ca2+ salts with carbonate sources, rapid or staged carbonation, and solvothermal or hydrothermal routes. Emulsion or microemulsion techniques can yield porous or hollow particles. Functionalization steps tailor dispersibility in water or organic media and enable conjugation with drugs, proteins, or targeting ligands.

Key properties include high surface area, tunable porosity, and pH-dependent solubility. In aqueous environments, dissolution releases Ca2+ and CO3 2-, with rate depending on particle size, polymorph, and coatings. Thermal behavior varies by polymorph and additives.

Applications span drug delivery and gene therapy as carriers, bone graft substitutes and dental materials, filler agents in polymers, and adsorbents or catalysts in environmental remediation. Research continues on scalable production, biocompatibility, and precise control over phase, size, and surface chemistry.

Safety and environmental considerations reflect those of other calcium carbonate nanoparticles: low bulk toxicity but potential inhalation risks, accumulation concerns, and regulatory considerations for nanomaterials.