Antiresorpní

Antiresorpní is a term derived from the Czech language, meaning "anti-resorptive" in English. It refers to substances or interventions that inhibit or reduce the resorption or breakdown of tissues, particularly in the context of bone health. The concept is primarily relevant in medical and dental fields, especially concerning diseases characterized by excessive tissue resorption.

In bone metabolism, antiresorptive agents are used to prevent or slow down the loss of bone density. These agents include bisphosphonates, denosumab, and selective estrogen receptor modulators (SERMs), which act by inhibiting osteoclast-mediated bone resorption. Such medications are commonly prescribed for conditions like osteoporosis, Paget's disease, and metastatic bone disease to maintain bone strength and reduce fracture risk.

In dentistry, antiresorpní measures are employed to manage and prevent root resorption, a process where the body resorbs dental roots often after trauma or orthodontic treatment. Therapeutic strategies may involve medications or interventions that inhibit osteoclastic activity to preserve dental structures.

The term "antiresorpní" also encompasses other applications where tissue resorption needs to be controlled or minimized, including certain strategies in regenerative medicine and implantology. Its use aims to maintain tissue integrity and functionality, preventing undesirable tissue loss.

Overall, antiresorpní interventions are vital in managing conditions associated with excessive tissue resorption, contributing to tissue preservation and improved clinical outcomes.