Androgeneettisyyteen

Androgeneettisyyteen refers to the genetic predisposition to developing androgenetic alopecia, also known as male-pattern baldness or female-pattern hair loss. This condition is characterized by a progressive thinning of hair, typically on the scalp. In men, it often manifests as a receding hairline and thinning at the crown, while in women, it usually presents as diffuse thinning over the top of the scalp with a preserved frontal hairline.

The development of androgeneettisyyteen is primarily influenced by genetic factors inherited from both parents, and it is mediated by androgens, particularly dihydrotestosterone (DHT). DHT binds to androgen receptors in hair follicles, leading to miniaturization of these follicles. Over time, the hair shafts produced by these miniaturized follicles become shorter, finer, and less pigmented, eventually ceasing to grow altogether. The sensitivity of hair follicles to DHT varies among individuals, which explains the differing patterns and severity of hair loss. While commonly associated with men, androgeneettisyyteen also affects women, though the hormonal mechanisms and presentation can differ. Research continues to identify specific genes and their roles in this heritable trait.