warfarinnál
Warfarinnál is a synthetic oral anticoagulant primarily used to prevent and treat thromboembolic disorders, such as deep vein thrombosis, pulmonary embolism, and atrial fibrillation-related stroke. It functions as a vitamin K antagonist, inhibiting the liver’s synthesis of vitamin K-dependent clotting factors (II, VII, IX, and X), thereby reducing blood coagulation.
The drug was first synthesized in the 1940s as a rodenticide before its medical applications were discovered.
Common side effects include bleeding, which can range from minor bruising to life-threatening hemorrhage. Regular monitoring
Contraindications include active bleeding, severe liver disease, and pregnancy (due to potential fetal harm). Alternatives like