vevssamspill
Vevssamspill is a term used in biology to describe the coordinated communication between different tissue components, including parenchymal cells, stromal cells, and the extracellular matrix (ECM). The concept emphasizes that tissue function emerges from interactions across cellular and extracellular elements rather than from isolated cell types. It covers both biochemical signaling and biophysical cues.
Mechanisms include paracrine and autocrine signaling, ligand-receptor interactions, and the release of extracellular vesicles that shuttle
Vevssamspill operates throughout development, tissue maintenance, and repair. In organogenesis, coordinated signaling between epithelial and mesenchymal
Researchers study vevssamspill using co-culture systems, organoids, imaging of signaling gradients, and computational models that integrate