ventromedialorbitofrontal
The ventromedial orbitofrontal cortex (VMOFC) is a subregion of the orbitofrontal cortex, located on the ventral and medial surface of the frontal lobe. It is part of the ventral prefrontal cortex and is commonly described together with adjacent medial OFC regions as the ventromedial prefrontal/orbitofrontal circuitry.
Functions include encoding the subjective value of rewards and punishments, integrating sensory, affective, and contextual information
Connectivity: input to the region comes from the amygdala, hippocampus, sensory cortices, and other limbic structures;
Clinical relevance: studies show that damage or dysfunction in the ventromedial OFC can impair decision making,
Research notes: the VMOFC is often discussed in the context of the broader orbitofrontal cortex and ventromedial