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substanceabuse

Substance abuse refers to the harmful or problematic pattern of using psychoactive substances, including alcohol, illicit drugs, and prescription medications, that leads to clinically significant impairment or distress. In many clinical and public health contexts, substance abuse is described using criteria that include excessive use, persistent desire or unsuccessful efforts to cut down, neglect of major responsibilities, and continued use despite social or interpersonal problems. The term is often used interchangeably with substance use disorder, which under DSM-5-TR is characterized by a problematic pattern of use with at least two of eleven criteria occurring within a 12-month period.

Substance use disorders affect people across ages and settings. Risk factors include genetic susceptibility, early exposure,

Common targets are alcohol, opioids, cannabis, stimulants, sedatives, and prescription medications when misused. Some individuals experience

Health consequences include injuries, infectious diseases, cardiovascular and liver conditions, mental health disorders, and overdose. Social

Assessment uses screening tools such as AUDIT or CAGE, plus clinical interviews and, when indicated, laboratory

Prevention and policy emphasize harm reduction, education, early intervention, and reducing stigma. Public health approaches include

trauma,
mental
illness,
social
environment,
and
availability
of
drugs.
The
course
can
be
episodic
or
chronic
and
may
involve
withdrawal,
tolerance,
craving,
and
relapse.
use
without
dependence,
while
others
develop
addiction
or
dependence
with
compulsive
seeking
and
use
despite
harm.
effects
may
involve
employment
problems,
legal
issues,
strained
relationships,
and
housing
instability.
tests.
Treatments
combine
pharmacotherapy
(opioid
agonists
like
methadone
or
buprenorphine
for
opioid
use
disorder;
naltrexone,
acamprosate
for
alcohol;
methadone,
buprenorphine,
or
naltrexone
for
others)
with
psychosocial
therapies
(motivational
interviewing,
cognitive-behavioral
therapy,
contingency
management).
Access
to
care
and
integrated
care
for
co-occurring
disorders
improves
outcomes.
increasing
access
to
evidence-based
treatment,
supporting
recovery
services,
and
safe-use
education.