povidonaiodo
Povidone-iodine, commonly referred to as povidone-iodine or PVP-I, is an antiseptic formed by complexing iodine with polyvinylpyrrolidone. The complex releases iodine gradually, providing broad-spectrum antimicrobial activity against bacteria, viruses, fungi, and some protozoa. It is used for skin disinfection before surgery, wound cleansing, and as a topical antiseptic for minor cuts, abrasions, burns, and mucous membranes. It is also employed in some mouthwashes and throat sprays, and in preoperative preparation of the skin.
Formulations of povidone-iodine include aqueous solutions, ointments, and scrubs, typically marketed in concentrations around 5–10% povidone-iodine.
Mechanism of action involves iodine penetrating microbial cells and inactivating proteins and nucleic acids, leading to
Safety and precautions: topical povidone-iodine is generally safe for short-term use on intact skin but can