picaridin

Picaridin, also marketed as icaridin in Europe, is a synthetic insect repellent used to deter mosquitoes, ticks, and other biting insects. It was developed as an alternative to DEET and is available in a range of formulations worldwide. Picaridin belongs to the piperidine class of compounds and is designed for skin application to reduce the risk of insect-borne disease transmission.

Compared with DEET at similar concentrations, picaridin offers comparable protection against a broad spectrum of insects, with some users reporting less odor and a lighter, less greasy feel on the skin. Typical consumer products contain 5–20% picaridin and provide several hours of protection, depending on concentration, exposure, and activity. Picaridin is generally stable on clothing and can be used on skin as directed by product labels.

Safety and tolerability: Overall, picaridin is considered to have a favorable safety profile. Adverse effects are uncommon but can include mild skin irritation or dermatitis in sensitive individuals. It is usually well tolerated in children and adults when used according to directions. Users should avoid applying to broken or irritated skin, contact with eyes or mucous membranes, and should wash treated skin after returning indoors or before eating. Do not ingest the product and keep it out of reach of children.

Regulatory status and use: Picaridin-containing products are registered in many jurisdictions, including the United States and the European Union, for skin application. Labeling typically specifies age recommendations (often children two months and older) and guidance on reapplication intervals. It is commonly available in sprays, lotions, and wipes and can be used on clothing in addition to exposed skin, unless otherwise directed.