neurotmesise

Neurotmesis is a term used in medicine, specifically in the field of neurology and orthopedics, to describe a severe nerve injury. It is the most serious category of nerve damage according to the Seddon classification of nerve injuries, which also includes neurapraxia and axonotmesis. In neurotmesis, the nerve fiber and its surrounding connective tissue sheath are completely severed. This means there is a total loss of continuity of the nerve.

The primary consequence of neurotmesis is a complete loss of motor and sensory function distal to the site of injury. Because the nerve has been physically divided, the nerve fibers are no longer able to conduct electrical impulses across the gap. Recovery from neurotmesis is often poor and requires surgical intervention. Surgical repair, such as nerve grafting or direct nerve repair, is necessary to bridge the gap and allow for potential regeneration. Even with successful surgery, the functional recovery can be lengthy and may be incomplete, with residual weakness or sensory deficits often persisting. The prognosis depends on various factors including the distance of the nerve gap, the type of nerve involved, and the success of the surgical repair.