mutatoren
Mutatoren is the plural form of mutator in genetics, used to describe factors that increase the rate at which mutations occur in an organism’s genome. In this sense, mutatoren can refer to specific genetic alleles, gene defects, or physiological states that elevate mutational load. A common context is the mutator phenotype, where the overall mutation rate is higher than normal due to impaired DNA replication fidelity or defective DNA repair pathways.
Mechanisms often involve defects in DNA repair systems or in proofreading during replication. In bacteria, mutatoren
Evolutionary and medical relevance is significant. Mutatoren can accelerate adaptation to changing environments, such as antibiotic
See also: mutator phenotype, mutator allele, mutation rate, DNA repair, mismatch repair, SOS response, antimutator. In