methoxyfenozide

Methoxyfenozide is a synthetic insecticide classified as an insect growth regulator (IGR). It acts as a non-steroidal agonist of the ecdysone receptor, mimicking the molting hormone ecdysone. In susceptible Lepidoptera larvae, this interaction induces premature or abnormal molting, leading to developmental failure and larval death. The mode of action is largely selective for caterpillar pests, with relatively low toxicity to many non-target organisms outside Lepidoptera.

The product is used to control caterpillar pests on a range of crops, including deciduous fruit trees (such as apples, pears, and stone fruits), vegetables (for example tomatoes and cucumbers), and some ornamentals. Common targets include codling moth, oriental fruit moth, leafrollers, armyworms, and related pests. Because it interferes with insect development rather than directly poisoning adults, methoxyfenozide is often integrated into broader pest management programs and used in rotation with other modes of action to mitigate resistance risk.

Applications are typically made as foliar sprays or soil/root treatments, depending on the crop and formulation. Methoxyfenozide is marketed in various formulations, including emulsifiable concentrates and water-dispersible granules. The product generally has low acute toxicity to mammals and a relatively favorable environmental profile, though risks to non-target Lepidoptera and pollinators can occur if applications are made during flowering or in bloom zones.

Regulatory status and residue considerations vary by country and crop; users should follow the product label and local guidelines. Resistance management recommendations emphasize rotating with products of different modes of action and monitoring pest populations.