ligandnyitott
Ligandnyitott is a Hungarian term used in biochemistry and structural biology to describe the ligand-open state of a protein or complex. This state refers to a conformational arrangement that occurs after ligand binding, in which a pore or channel becomes open or an active site becomes accessible, enabling function such as ion conductance or catalysis. The ligandnyitott state is a key part of the activation mechanism for many biomolecules and is typically discussed in contrast to ligand-closed or apo forms.
In Hungarian-language literature, ligandnyitott is often described with English equivalents such as ligand-open state or ligand-activated
Studies of the ligandnyitott state employ a range of methods, including electrophysiology to assess functional opening,
See also: ligand-gated ion channel, allostery, conformational change, activation, induced fit.