letrosool

Letrosool is not a standard name in major medical references and may be a misspelling or regional variant of letrozole, a non-steroidal aromatase inhibitor used in cancer therapy. If you meant letrozole, the following summary outlines its general medical use and properties.

Letrozole works by inhibiting aromatase, the enzyme that converts androgens to estrogen. By lowering estrogen levels, the drug can slow the growth of estrogen receptor–positive tumors and may improve progression-free survival in certain settings.

Medical uses include the treatment of hormone receptor–positive breast cancer in postmenopausal women, commonly as adjuvant therapy after surgery or for treatment of metastatic or locally advanced disease. It is used in various countries as extended adjuvant therapy in selected patients. Letrozole is also used off-label to induce ovulation in some infertility treatments, particularly in women who have ovulatory dysfunction.

Pharmacokinetics and administration: letrozole is taken orally and is generally well absorbed. It has a relatively long elimination half-life and is primarily metabolized in the liver, with excretion via urine and feces. Dosing is individualized and should follow clinical guidelines.

Adverse effects and safety: common side effects include hot flashes, sweating, fatigue, headaches, arthralgia or myalgia, and nausea. Long-term use can reduce bone mineral density, increasing fracture risk, so bone health monitoring is often advised. The drug is not recommended during pregnancy (category X) and is typically avoided in premenopausal women unless ovarian suppression is used. Caution is advised in hepatic impairment and during drug interactions.

Interactions and considerations: letrozole is metabolized by hepatic enzymes and may interact with strong CYP inhibitors or inducers. It should not be combined with estrogen-containing therapies, and concurrent use with tamoxifen is generally avoided; clinicians may sequence therapies instead. If you intended to learn about letrozole, this information reflects its established profile.