endossomal
Endossomal refers to endosomes and endosome-related processes in eukaryotic cells. The standard term is endosomal; endossomal appears in some literature as an alternative spelling or inflected form and is generally understood to relate to endosomal biology.
Endosomes are membrane-bound compartments that internalize extracellular material and membrane proteins. Within the endossomal system, early
Functions and pathways include endossomal trafficking in receptor downregulation, nutrient signaling, antigen processing, and intracellular routing
Clinical and research relevance: endosomal-lysosomal dysfunction is linked to neurodegenerative diseases such as Alzheimer's and Parkinson's
Research methods include fluorescence tagging of markers (such as EEA1, Rab5, Rab7, and LAMP1), live-cell imaging,