comedogênese

Comedogenesis refers to the process by which comedones, commonly known as blackheads and whiteheads, are formed. These are non-inflammatory lesions that are a hallmark of acne. The development of comedones begins with an overproduction of sebum, the oil naturally produced by the skin's sebaceous glands. This excess sebum, combined with dead skin cells, can clog the opening of a hair follicle, also known as a pore.

When this blockage occurs within a closed follicle, a whitehead is formed. The trapped sebum and dead cells are covered by a thin layer of skin, giving it a white or flesh-colored appearance. In contrast, a blackhead forms when the follicle opening remains open. The trapped sebum and dead cells are exposed to the air, causing oxidation. This oxidation process turns the contents of the pore dark, resulting in the characteristic black appearance. It's important to note that the black color is not due to dirt.

Factors contributing to comedogenesis include hormonal changes, particularly during puberty, menstruation, or pregnancy, which can stimulate increased sebum production. Genetics also play a role, as some individuals are predisposed to developing acne and comedones. Certain cosmetic products, especially those that are comedogenic, can also contribute to pore blockage. Lifestyle factors like stress and diet are sometimes implicated, though their direct role is a subject of ongoing research. Understanding comedogenesis is key to developing effective strategies for acne management and prevention.