TBEVSib
TBEV-Sib, short for tick-borne encephalitis virus Siberian subtype, is one of the lineages of Tick-borne encephalitis virus (TBEV), a positive-sense RNA virus in the Flaviviridae family. It is distinct from other TBEV subtypes such as the European and Far Eastern lineages, with genetic differences predominantly in the envelope (E) protein used for phylogenetic classification.
Geographic distribution and vectors are centered in Siberia and northern Asia, with occurrences across parts of
Clinically, TBEV-Sib infections can range from asymptomatic to neuroinvasive disease. A biphasic illness is common: an
Diagnosis relies on laboratory testing, primarily serology for TBEV-Sib–specific IgM and IgG in serum or cerebrospinal
Prevention focuses on tick avoidance and vaccination. Licensed TBE vaccines provide cross-protection against multiple subtypes and