RotationsThromboelastometrie
RotationsThromboelastometrie, commonly referred to as ROTEM, is a viscoelastic hemostasis assay that evaluates the dynamic process of clot formation and dissolution in whole blood. It provides a real-time, graphical representation of coagulation from initiation through stabilization to fibrinolysis, enabling rapid assessment of a patient’s coagulation status.
In ROTEM, a blood sample is placed in a cup and a component (such as a pin
Assays used in ROTEM include EXTEM (extrinsic pathway activation with tissue factor), INTEM (intrinsic pathway activation
Key parameters in ROTEM are CT (clotting time), CFT (clot formation time), the α-angle, and MCF (maximum
Clinical use and interpretation: ROTEM is widely used in perioperative settings, major trauma, obstetrics, liver transplantation,
Limitations include the need for trained operators, device variability, and the fact that ROTEM complements but