RhoAROCKdriven
RhoAROCKdriven is a term used in cell biology to describe cellular processes and behaviors predominantly controlled by the RhoA–ROCK signaling axis. The name reflects the idea that signaling through RhoA and its downstream effector ROCK governs cytoskeletal dynamics and force generation that shape cell behavior.
Mechanistically, activation of RhoA leads to activation of ROCK, which phosphorylates myosin light chain (MLC) directly
Biological roles of RhoAROCKdriven processes include contributions to development, wound healing, and tissue remodeling, where coordinated
Evidence from experiments supports the central role of this axis: pharmacological inhibitors like Y-27632 or fasudil
RhoAROCKdriven is a descriptive, non-formal label that emphasizes pathway-dominated behavior rather than a standalone entity. It