Retinil

Retinil is a term that appears in some contexts to refer to retinoid-related compounds derived from retinol, particularly retinyl esters. It is not an established IUPAC name, and the more precise terms in chemistry and nutrition are retinol, retinal, retinoic acid, and various retinyl esters such as retinyl palmitate and retinyl acetate. The root retin- denotes vitamin A derivatives, with the suffixes indicating different functional forms.

Chemically, retinyl compounds are lipophilic derivatives of retinol. Retinyl esters are fatty acid esters of retinol, serving as storage and dietary forms of vitamin A. In the body, retinyl esters are hydrolyzed to retinol in the intestine, transported to the liver, and can be oxidized to retinal and then to retinoic acid, a signaling molecule that regulates gene expression.

Biological role and metabolism: Vitamin A is essential for vision, immune function, and development. Retinol and retinal participate in the visual cycle, while retinoic acid acts as a hormone-like regulator of transcription. The body maintains stores of retinyl esters in the liver, from which retinol can be mobilized when needed.

Uses and applications: Retinyl esters are commonly used as dietary supplements and as cosmetic ingredients. Retinyl palmitate and retinyl acetate are widely found in fortified foods and skincare products. In cosmetics, they serve as sources of vitamin A and as anti-inflammatory and antioxidant additives, though their efficacy can depend on formulation and skin type.

Safety and regulation: Vitamin A fat-soluble compounds can be toxic at high doses, especially during pregnancy. Topical retinoids may cause irritation or photosensitivity. Regulatory guidelines govern intake levels, labeling, and cosmetic use in different jurisdictions.

See also: Vitamin A, Retinol, Retinyl esters, Retinoic acid.