Pediatrisilla

Pediatrisilla is a genus of bacteria belonging to the family Enterobacteriaceae. It is a Gram-negative, facultatively anaerobic, rod-shaped bacterium that is commonly found in the gastrointestinal tract of humans and animals. The genus was first described in 1984 and is named after the Latin word "pediatris," which means "child," reflecting its frequent isolation from pediatric patients.

Pediatrisilla species are known to be opportunistic pathogens, meaning they can cause infections in individuals with compromised immune systems, such as newborns, elderly patients, and those undergoing medical treatments. Common infections associated with Pediatrisilla include urinary tract infections, wound infections, and sepsis. The genus is characterized by its ability to produce urease, an enzyme that catalyzes the hydrolysis of urea to ammonia and carbon dioxide, which can contribute to the formation of urinary stones.

Diagnosis of Pediatrisilla infections typically involves the isolation of the bacterium from clinical specimens, such as urine, blood, or wound swabs, using standard microbiological techniques. Treatment often involves the administration of appropriate antibiotics, such as third-generation cephalosporins or carbapenems, depending on the specific species and the severity of the infection. Due to the increasing prevalence of antibiotic resistance, the choice of antibiotics and the duration of treatment should be guided by local antimicrobial susceptibility patterns and clinical guidelines.

Pediatrisilla species are not typically transmitted from person to person and are generally considered to be part of the normal flora of the gastrointestinal tract. However, their opportunistic nature and the potential for antibiotic resistance make them an important consideration in clinical microbiology and infectious disease management. Further research is needed to better understand the epidemiology, pathogenesis, and treatment of Pediatrisilla infections.