NSGCT
Non-seminomatous germ cell tumor (NSGCT) is a subset of testicular germ cell tumors defined by non-seminomatous histology. NSGCTs include embryonal carcinoma, yolk sac tumor, choriocarcinoma, teratoma, and mixed forms. They typically affect young men and often present as a painless testicular mass.
Unlike seminoma, NSGCTs frequently elevate serum tumor markers such as alpha-fetoprotein (AFP) and beta-hCG; teratoma usually
Staging uses TNM and, for metastatic disease, the IGCCCG risk groups (good, intermediate, poor). Localized disease
Advanced NSGCT or extensive retroperitoneal disease is treated with platinum-based chemotherapy, most commonly BEP (bleomycin, etoposide,
Fertility considerations are important; many patients are young and may bank sperm before treatment. With current