Lipohypertrophien

Lipohypertrophien refers to an abnormal enlargement of adipose (fat) tissue, typically occurring in individuals with diabetes, particularly those who use insulin. This condition is characterized by the excessive accumulation of fat in specific areas of the body, often at injection sites, leading to lumpy or uneven skin contours. Unlike lipodystrophy, which involves the loss of fat tissue, lipohypertrophien involves fat deposition, creating raised, rubbery masses beneath the skin.

The exact cause of lipohypertrophien is not fully understood, but it is strongly associated with insulin use, particularly in people with insulin-dependent diabetes mellitus. Frequent insulin injections into the same site can stimulate fat cell proliferation, contributing to the development of these growths. Risk factors include long-term insulin therapy, improper injection techniques, and inconsistent injection site rotation.

Symptoms of lipohypertrophien include visible lumps or swelling under the skin, often in areas where insulin is commonly injected, such as the abdomen, thighs, or buttocks. These growths may be painless but can interfere with insulin absorption, potentially leading to poor glycemic control. Diagnosis is typically made through physical examination, though imaging techniques like ultrasound may be used to confirm the presence of fat accumulation.

Prevention and management of lipohypertrophien involve proper insulin injection techniques, including rotating injection sites systematically to avoid repeated use of the same area. Patients are advised to avoid injecting into visibly swollen or lumpy regions. If lipohypertrophien develops, consulting a healthcare provider for guidance on injection practices and potential adjustments to insulin regimens is recommended. In severe cases, surgical removal of the excess fat may be considered, though this is less common due to the risk of recurrence. Maintaining overall diabetes management and monitoring injection sites regularly can help minimize complications associated with this condition.