Klierhyperplasie

Klierhyperplasie, also known as glandular hyperplasia, refers to an increase in the number of cells within a gland, leading to an enlargement of the gland itself. This condition is characterized by the proliferation of glandular tissue and can occur in various endocrine and exocrine glands throughout the body. It is often a response to hormonal stimuli or other physiological factors.

In the thyroid gland, klierhyperplasie can manifest as diffuse or nodular enlargement, frequently associated with conditions like Graves' disease or autonomous adenomas. This hyperplasia typically results from hyperactivity of the gland due to elevated stimulation by thyroid-stimulating hormone (TSH) or other factors. In other glands, such as the prostate, hyperplasia may contribute to benign prostatic hyperplasia (BPH), causing urinary symptoms.

Pathologically, klierhyperplasie is distinguished from neoplasia by its organized and regulated cell growth, although it may sometimes mimic tumor formation clinically or radiologically. It is generally considered a benign process and may be reversible upon removal of the stimulating factors or treatment of underlying causes.

The diagnosis of glandular hyperplasia often involves imaging studies, hormone level assessments, and histopathological examination. Treatment strategies depend on the gland involved and the severity of the hyperplasia. In some cases, observation and monitoring are sufficient, while others may require medical or surgical intervention.

Overall, klierhyperplasie is an important clinical entity that reflects adaptive or reactive changes in glandular tissues, underlying various physiological and pathological conditions. Understanding its mechanisms and implications is essential for proper diagnosis and management.