Intravascularis

Intravascularis is a rare, progressive, and often fatal disease characterized by the accumulation of iron in the blood vessels, leading to their destruction. It is primarily associated with the consumption of certain types of mushrooms, particularly the fly agaric (Amanita muscaria) and the death cap (Amanita phalloides), which contain the toxin amatoxin. The disease was first described in the 1950s and is believed to be caused by the accumulation of iron in the blood vessels, leading to their destruction and subsequent organ failure.

The symptoms of intravascularis typically begin within a few days to a few weeks after consuming the toxic mushrooms and may include fever, chills, muscle pain, and joint pain. As the disease progresses, it can lead to organ failure, including kidney failure, liver failure, and heart failure. In severe cases, intravascularis can be fatal within a few days of the onset of symptoms.

There is no specific treatment for intravascularis, and supportive care is the primary focus of management. This may include fluid replacement, blood pressure support, and dialysis in cases of kidney failure. In some cases, plasma exchange may be used to remove the toxic substances from the blood. However, the prognosis for intravascularis is generally poor, with a high mortality rate.

Prevention of intravascularis involves avoiding the consumption of toxic mushrooms and being aware of the symptoms of the disease. If someone is suspected of having consumed toxic mushrooms and is experiencing symptoms, medical attention should be sought immediately.