Indoxacarb

Indoxacarb is an insecticide belonging to the oxadiazine chemical class. It acts by blocking sodium ion channels in insect nerve cells, leading to paralysis and death. This mode of action is distinct from many other insecticide classes, making it useful in managing insect populations that have developed resistance to other chemicals. Indoxacarb is effective against a wide range of insect pests, particularly Lepidoptera (moths and butterflies) and some Coleoptera (beetles) and Diptera (flies).

The insecticide is typically formulated as an emulsifiable concentrate, suspension concentrate, or wettable powder for agricultural applications. It is applied to crops such as cotton, corn, vegetables, and fruits to control pests like bollworms, corn earworms, and diamondback moths. Indoxacarb exhibits both contact and ingestion activity. Its efficacy can be influenced by factors such as temperature and light.

In terms of environmental fate, indoxacarb can be degraded by microbial activity in soil and water. Its persistence varies depending on environmental conditions. While generally considered to have moderate toxicity to mammals, birds, and fish, it can be toxic to certain non-target insects, including beneficial predators and pollinators, if not applied carefully. Integrated pest management programs often incorporate indoxacarb in rotation with other insecticides to help prevent the development of resistance.