INRG
INRG stands for the International Neuroblastoma Risk Group, a global collaborative network of pediatric oncology centers. The group aims to standardize risk assessment, staging, and treatment planning for neuroblastoma, and to promote international data sharing and research. Its guidelines are designed to be applicable across diverse health systems to improve outcomes and enable meaningful comparisons of care.
History and purpose. The INRG initiative emerged in the early 2000s, culminating in the INRG staging system
Staging and risk classification. INRGSS categorizes tumors using stages that include localized disease without IDRFs (L1),
Genetics and biology. In addition to MYCN amplification, other genetic features—such as 11q abnormalities and DNA
Data resources and impact. The INRG Database (IDB) serves as a centralized repository of pretreatment and outcome