Hemin
Hemin, also known as ferriprotoporphyrin IX chloride, is the ferric (iron(III)) form of heme, the porphyrin-based prosthetic group found in many proteins. In hemin, the central iron is six-coordinate, with four nitrogens from the porphyrin ring and a sixth ligand, commonly a chloride ion in the isolated compound; within proteins, that sixth coordination site is typically occupied by a histidine residue or a water molecule.
Chemically, hemin is a dark, relatively insoluble solid that tends to aggregate in water. It is more
Natural occurrence and applications: Hemin is the ferric component of heme and is encountered as a breakdown
Medical use: Hemin preparations are used medically to treat acute porphyrias. Intravenous hemin (often referred to
Safety and handling: Hemin is sensitive to light and can cause injection-site reactions and other adverse effects